Zahinoor Ismail


University of Calgary


[email protected]

Research Keywords

Mild Behavioral Impairment (MBI), Subjective Cognitive Decline, Neuropsychiatric Symptoms, neuroimaging and biomarkers, Mild Cognitive Impairment, rating scale development, fMRI, systematic reviews and meta-analyses, pharmacotherapy

Additional Information

Lab Methodologies
  • MRI analysis (structural and functional)
  • S-CitAD study (escitalopram for agitation in Alzheimer’s)
  • FAVR MBI study (observational study of MBI and incident cognitive decline and dementia)


Biographical Information

Early dementia detection, dementia clinical trials and intervention/observational studies, the association of neuropsychiatric symptoms and neurodegenerative disease, rating scale development (www.MBItest.org).

Most Cited Publications

Ismail Z, Smith EE, Geda Y, Sultzer D, Brodaty H, Smith G, Ag├╝era-Ortiz L, Sweet R, Miller D, Lyketsos CG, ISTAART Neuropsychiatric Symptoms Professional Interest Area., "Neuropsychiatric symptoms as early manifestations of emergent dementia: Provisional diagnostic criteria for mild behavioral impairment." Alzheimer's & dementia : the journal of the Alzheimer's Association 12,2 (2016 Feb): 195-202
Porsteinsson AP, Drye LT, Pollock BG, Devanand DP, Frangakis C, Ismail Z, Marano C, Meinert CL, Mintzer JE, Munro CA, Pelton G, Rabins PV, Rosenberg PB, Schneider LS, Shade DM, Weintraub D, Yesavage J, Lyketsos CG, CitAD Research Group., "Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial." JAMA 311,7 (2014 Feb 19): 682-91
Ismail Z, Elbayoumi H, Fischer CE, Hogan DB, Millikin CP, Schweizer T, Mortby ME, Smith EE, Patten SB, Fiest KM, "Prevalence of Depression in Patients With Mild Cognitive Impairment: A Systematic Review and Meta-analysis." JAMA psychiatry 74,1 (2017 Jan 1): 58-67