About

Name

Stephanie Borgland

University

University of Calgary

Website

http://www.hbi.ucalgary.ca/profiles/dr-stephanie-borgland

Email

[email protected]

Research Keywords

neural mechanisms of overeating, drug abuse induced neuroplasticity, early life stress and reward circuitry, neural mechanisms of compulsive behaviours, electrophysiology, synaptic physiology, neuropeptides, VTA, dopamine, orbitofrontal cortex, motivation, learning, reward, addiction

Additional Information

Lab Methodologies
  • brain slice electrophysiology
  • voltammetry
  • immunohistochemistry
  • optogenetics
  • behaviour
  • biochemistry
Apparatus
  • electrophysiological rig
  • behavioural operant chambers
  • slice voltammetry
  • in vivo voltammetry
Biographical Information

Plasticity associated with addiction and obesity in neural circuits underlying cues that predict rewards, motivation and reward valuation.

Most Cited Publications

Baimel C, Lau BK, Qiao M, Borgland SL, "Projection-Target-Defined Effects of Orexin and Dynorphin on VTA Dopamine Neurons." Cell reports 18,6 (2017 Feb 7): 1346-1355
Bowen GP, Borgland SL, Lam M, Libermann TA, Wong NC, Muruve DA, "Adenovirus vector-induced inflammation: capsid-dependent induction of the C-C chemokine RANTES requires NF-kappa B." Human gene therapy 13,3 (2002 Feb 10): 367-79
Liu S, Globa AK, Mills F, Naef L, Qiao M, Bamji SX, Borgland SL, "Consumption of palatable food primes food approach behavior by rapidly increasing synaptic density in the VTA." Proceedings of the National Academy of Sciences of the United States of America 113,9 (2016 Mar 1): 2520-5