About

Name

Stephanie Borgland

University

University of Calgary

Website

http://www.hbi.ucalgary.ca/profiles/dr-stephanie-borgland

Email

[email protected]

Research Keywords

neural mechanisms of overeating, drug abuse induced neuroplasticity, early life stress and reward circuitry, neural mechanisms of compulsive behaviours, electrophysiology, synaptic physiology, neuropeptides, VTA, dopamine, orbitofrontal cortex, motivation, learning, reward, addiction

Additional Information

Lab Methodologies
  • brain slice electrophysiology
  • voltammetry
  • immunohistochemistry
  • optogenetics
  • behaviour
  • biochemistry
Apparatus
  • electrophysiological rig
  • behavioural operant chambers
  • slice voltammetry
  • in vivo voltammetry
Biographical Information

Plasticity associated with addiction and obesity in neural circuits underlying cues that predict rewards, motivation and reward valuation.

Most Cited Publications

Burma NE, Bonin RP, Leduc-Pessah H, Baimel C, Cairncross ZF, Mousseau M, Shankara JV, Stemkowski PL, Baimoukhametova D, Bains JS, Antle MC, Zamponi GW, Cahill CM, Borgland SL, De Koninck Y, Trang T, "Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents." Nature medicine 23,3 (2017 Mar): 355-360
Baimel C, Lau BK, Qiao M, Borgland SL, "Projection-Target-Defined Effects of Orexin and Dynorphin on VTA Dopamine Neurons." Cell reports 18,6 (2017 Feb 7): 1346-1355
Naef L, Pitman KA, Borgland SL, "Mesolimbic dopamine and its neuromodulators in obesity and binge eating." CNS spectrums 20,6 (2015 Dec): 574-83