About

Name

Stephanie Borgland

University

University of Calgary

Website

http://www.hbi.ucalgary.ca/profiles/dr-stephanie-borgland

Email

[email protected]

Research Keywords

neural mechanisms of overeating, drug abuse induced neuroplasticity, early life stress and reward circuitry, neural mechanisms of compulsive behaviours, electrophysiology, synaptic physiology, neuropeptides, VTA, dopamine, orbitofrontal cortex, motivation, learning, reward, addiction

Additional Information

Lab Methodologies
  • brain slice electrophysiology
  • voltammetry
  • immunohistochemistry
  • optogenetics
  • behaviour
  • biochemistry
Apparatus
  • electrophysiological rig
  • behavioural operant chambers
  • slice voltammetry
  • in vivo voltammetry
Biographical Information

Plasticity associated with addiction and obesity in neural circuits underlying cues that predict rewards, motivation and reward valuation.

Most Cited Publications

Burma NE, Bonin RP, Leduc-Pessah H, Baimel C, Cairncross ZF, Mousseau M, Shankara JV, Stemkowski PL, Baimoukhametova D, Bains JS, Antle MC, Zamponi GW, Cahill CM, Borgland SL, De Koninck Y, Trang T, "Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents." Nature medicine 23,3 (2017 Mar): 355-360
Baimel C, Borgland SL, "Orexin Signaling in the VTA Gates Morphine-Induced Synaptic Plasticity." The Journal of neuroscience : the official journal of the Society for Neuroscience 35,18 (2015 May 6): 7295-303
Liu S, Globa AK, Mills F, Naef L, Qiao M, Bamji SX, Borgland SL, "Consumption of palatable food primes food approach behavior by rapidly increasing synaptic density in the VTA." Proceedings of the National Academy of Sciences of the United States of America 113,9 (2016 Mar 1): 2520-5