Richard Frayne


University of Calgary




[email protected]

Research Keywords

brain imaging, vascular dementia, stroke, aging

Additional Information

Lab Methodologies
  • MR imaging protocol and sequence development for angiography, diffusion, perfusion, permeability, quantitative iron imaging, T1, T2 and T2* relaxometry, and susceptibility weighted imaging (SWI)
  • Large animal anesthesia, monitoring and surgical equipment
  • Pulse programming for a GE MR scanner
  • Large scale image processing and data management for clinical trials (CIPAC)
  • 3T MR Scanner
  • OEC 9800 C-arm

Most Cited Publications

Case NF, Charlton A, Zwiers A, Batool S, McCreary CR, Hogan DB, Ismail Z, Zerna C, Coutts SB, Frayne R, Goodyear B, Haffenden A, Smith EE, "Cerebral Amyloid Angiopathy Is Associated With Executive Dysfunction and Mild Cognitive Impairment." Stroke 47,8 (2016 Aug): 2010-6
Thrippleton MJ, Backes WH, Sourbron S, Ingrisch M, van Osch MJP, Dichgans M, Fazekas F, Ropele S, Frayne R, van Oostenbrugge RJ, Smith EE, Wardlaw JM, "Quantifying blood-brain barrier leakage in small vessel disease: Review and consensus recommendations." Alzheimer's & dementia : the journal of the Alzheimer's Association 15,6 (2019 Jun): 840-858
Frayne R, Goodyear BG, Dickhoff P, Lauzon ML, Sevick RJ, "Magnetic resonance imaging at 3.0 Tesla: challenges and advantages in clinical neurological imaging." Investigative radiology 38,7 (2003 Jul): 385-402