Paolo Federico


University of Calgary




[email protected]

Research Keywords

cortical and subcortical circuits underlying the generation of seizures in humans using EEG-functional MRI, MR analysis of seizure-related changes in brain structure and function; advanced EEG analytical?techniques, advanced EEG analytical?techniques, including the study of high frequency oscillations in humans

Additional Information

Lab Methodologies
  • Scanning subjects in MRI, fMRI and structural MRI data analysis


  • The 3.0T GE MRI magnet at the U of C Seaman Family MR Research Centre


Most Cited Publications

Farrell JS, Gaxiola-Valdez I, Wolff MD, David LS, Dika HI, Geeraert BL, Rachel Wang X, Singh S, Spanswick SC, Dunn JF, Antle MC, Federico P, Teskey GC, "Postictal behavioural impairments are due to a severe prolonged hypoperfusion/hypoxia event that is COX-2 dependent." eLife 5, (2016 Nov 22):
Farrell JS, Colangeli R, Wolff MD, Wall AK, Phillips TJ, George A, Federico P, Teskey GC, "Postictal hypoperfusion/hypoxia provides the foundation for a unified theory of seizure-induced brain abnormalities and behavioral dysfunction." Epilepsia 58,9 (2017 Sep): 1493-1501
Gaxiola-Valdez I, Singh S, Perera T, Sandy S, Li E, Federico P, "Seizure onset zone localization using postictal hypoperfusion detected by arterial spin labelling MRI." Brain : a journal of neurology 140,11 (2017 Nov 1): 2895-2911