cellular and molecular mechanisms underlying pathogensis in Alzheimer's disease, identification of new therapeutic targets (i.e. amylin receptors) for Alzheimer's Disease, bioenergetics and glycolytic mechanisms in neurodegeneration, Alzheimer's disease, beta amyloid, amylin, neurophysiology, cell cultures, animal models, LTP
Molecular mechanisms in Alzheimer’s disease pathogenesis. Development and testing of novel therapeutics for this condition.
Roles and Connections
Most Cited Publications
|Jhamandas JH, Li Z, Westaway D, Yang J, Jassar S, MacTavish D, "Actions of β-amyloid protein on human neurons are expressed through the amylin receptor." The American journal of pathology 178,1 (2011 Jan): 140-9|
|Jhamandas JH, Mactavish D, "β-Amyloid protein (Aβ) and human amylin regulation of apoptotic genes occurs through the amylin receptor." Apoptosis : an international journal on programmed cell death 17,1 (2012 Jan): 37-47|
|Alier K, Ma L, Yang J, Westaway D, Jhamandas JH, "Aβ inhibition of ionic conductance in mouse basal forebrain neurons is dependent upon the cellular prion protein PrPC." The Journal of neuroscience : the official journal of the Society for Neuroscience 31,45 (2011 Nov 9): 16292-7|