Fred Colbourne


University of Alberta




[email protected]

Research Keywords

Stroke, Neuroprotection, therapeutic hypothermia, intracerebral hemorrhage,, brain plasticity

Additional Information

Lab Methodologies
  • Stroke surgery
  • Telemetry recordings (temperature, blood pressure, EEG, and intracranial pressure)
  • Methods to induce systemic and brain-selective hypothermia
  • Behavioral methods (sensory, motor and cognitive tasks; rehabilitation methods such as enrichment and skills training)
  • Synchrotron imaging
  • Histology
  • Telemetry recording equipment (e.g., temperature measurement and control in awake and freely moving animals)
  • Ability to induce hypothermia in anesthetized and freely moving rodents

Roles and Connections

Primary Role


CAN Connections

Nervous System Injury

Looking For

Accepting graduate students, Accepting postdoctoral fellows

Most Cited Publications

Potter LE, Paylor JW, Suh JS, Tenorio G, Caliaperumal J, Colbourne F, Baker G, Winship I, Kerr BJ, "Altered excitatory-inhibitory balance within somatosensory cortex is associated with enhanced plasticity and pain sensitivity in a mouse model of multiple sclerosis." Journal of neuroinflammation 13,1 (2016 Jun 10): 142
Catuneanu A, Paylor JW, Winship I, Colbourne F, Kerr BJ, "Sex differences in central nervous system plasticity and pain in experimental autoimmune encephalomyelitis." Pain 160,5 (2019 May): 1037-1049
Almekhlafi MA, Colbourne F, Al Sultan AS, Goyal M, Demchuk AM, "Selective brain cooling: Let us have a moment of science." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 39,1 (2019 Jan): 182-183